one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected with bortezomib, a proteasome inhibitor Employed in the cure of many myeloma. Its synthesis or analyze is vital for guaranteeing the purity and security with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-1): A vital compound inside the synthesis of imatinib, a drug that targets precise kinds of cancer, like Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers such as breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is essential for optimizing the generation approach and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is made use of to deal with breast cancer, and these intermediates are involved with its generation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist Utilized in the remedy of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in managing cancers such as ovarian, breast, and lung cancer.
3. Other 2-deoxy-2 Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment method of colorectal most cancers and small mobile lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-82-9): This 1-AMINO-3-ADAMANTANOL compound is involved with the synthesis of adamantane derivatives, that have numerous programs, including antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-4 to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved with the synthesis of varied gluconic acid derivatives, which are used in food items, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication employed to control variety 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).